Metabolic syndrome are a major cause of mortalityĪnd morbidity in India and forecasted estimates in thisĭomain of research are scarcely reported in literature. Long-term cardiovascular complications in Or already diagnosed to have diabetes mellitus (HDL)-cholesterol, (4) elevated blood pressure (BP)Īnd (5) elevated fasting plasma glucose (FPG) Triglyceride (TG), (3) reduced high-density lipoprotein (1) elevated waist circumference (WC), (2) elevated More of the following five components are present: Metabolic syndrome is identified when three or Treatment Panel III (NCEP ATP III) has laidĭown guidelines for defining a typical patient of The National Cholesterol Education Program – Adult In aged individuals, affecting half of adults aged Moreover, metabolic syndrome is more prevalent Vulnerable to get coronary heart disease (CHD). Sex with metabolic syndrome were 1.5-2 times more InĪ community study, middle-aged people of either Greater risk of developing type 2 diabetes. People with metabolic syndrome have a fivefold That the metabolic syndrome is associated with anĪpproximate twofold increase in CVD. Various prospective analyses have reported Of type 2 diabetes and cardiovascular diseases Sensitivity that lead to a high risk for the development Metabolic syndrome is an array of lipid and nonlipidįactors of metabolic origin related to defects in insulin UKPDS risk engine, cardiovascular complications, metabolic syndrome Simulated projections of metabolic syndrome patients predict serious life-threatening cardiovascular consequences in the representative cohort of patients in western India. The relative risk (95% confidence interval) for coronary heart disease, fatal coronary heart disease, stroke and fatal stroke was 17.8 (12.98-19.99), 7 (6.7-7.2), 5.9 (4.0-6.6) and 4.7 (3.2-5.7), respectively. The absolute risk (95% confidence interval) for coronary heart disease, fatal coronary heart disease, stroke and fatal stroke for 10 years was 3.79 (1.5-3.2), 9.6 (6.8-10.7), 7.91 (6.5-9.9) and 3.57 (2.3-4.5), respectively. The data for each patient was processed using the United Kingdom Prospective Diabetes Study risk engine to calculate an estimate of the forecasted value for the cardiovascular complications after a period of 10 years. A projection for 10 simulated years was run on the engine and output was determined. The patients of metabolic syndrome were selected according to guidelines of National Cholesterol Education Program - Adult Treatment Panel III, modified National Cholesterol Education Program - Adult Treatment Panel III and International Diabetes Federation criteria. Patient level data was collated from 567 patients suffering from metabolic syndrome through structured interviews and physician records regarding the input variables, which were entered into the United Kingdom Prospective Diabetes Study risk engine. The aim of present investigation is to estimate the cardiovascular events associated with a representative Indian population of patients suffering from metabolic syndrome using United Kingdom Prospective Diabetes Study risk engine. Long-term cardiovascular complications in metabolic syndrome are a major cause of mortality and morbidity in India and forecasted estimates in this domain of research are scarcely reported in the literature.
0 kommentar(er)
